Third Ventricle Width Assessed by Transcranial Sonography as Predictor of Long-Term Cognitive Impairment
Non-invasive biomarkers of cognitive impairment are needed. We aim to evaluate transcranial sonographic markers as predictors of cognitive impairment in a prospective cohort.
Attenuated Brain Responses to Speech Sounds in Moderate Preterm Infants at Term Age
Recent findings have revealed that very preterm neonates already show the typical brain responses to place of articulation changes in stop consonants, but data on their sensitivity to other types of phonetic changes remains scarce.
Metacognition of Daily Self-Regulation Processes and Personality Traits in Borderline Personality Disorder
Patients with Borderline Personality Disorder (BPD) are characterized by impoverished self-regulatory mechanisms and self-image distortions. An intriguing question is to what extent BPD individuals develop accurate perceptions of their self-regulatory everyday functioning. Here, we tackle this issue evaluating their metacognitive abilities.
Kidney Function Changes and Their Relation With the Progression of Cerebral Small Vessel Disease and Cognitive Decline
We aimed to study whether worsening in markers of kidney function parallels the progression in cerebral small vessel disease (cSVD) and cognitive decline.
NEU Screen Shows High Accuracy in Detecting Cognitive Impairment in Older Persons Living With HIV
The NEUrocognitive (NEU) Screen is a practical tool proposed to screen for HIV-associated cognitive impairment in the clinical setting. This is a pencil-and-paper method that can be applied rapidly (≤10 minutes for administration) and has no copyright limitations. In this study, we aimed at investigating its diagnostic accuracy in an older population of persons living with HIV (PLWH), with cutoffs set at 30, 40, 50, and 60 years.
Functional and Structural Correlates of Working Memory Performance and Stability in Healthy Older Adults
Despite the well-described deleterious effects of aging on cognition, some individuals are able to show stability. Here, we aimed to describe the functional and structural brain characteristics of older individuals, particularly focusing on those with stable working memory (WM) performance, as measured with a verbal N-back task across a 2-year follow-up interval.
Resting-State Functional Connectivity Dynamics in Healthy Aging: An Approach Through Network Change Point Detection
This study aims at assessing the impact of age on the short-term temporal dynamics of the topological properties of the undirected and weighted whole-brain functional connectivity (FC) networks. We studied the association between the participant’s age and the number of significant change points detected through the Network Change Point Detection algorithm.
Plasticity as a Therapeutic Target for Improving Cognition and Behavior in Down Syndrome
Early intervention and environmental optimization have been central to management of Down syndrome (DS) and much of current treatment is still focused in strategies that involve early education plans. This approach has provided significant improvements for Down syndrome but it is not providing a full success.
Disruption of Posterior Brain Functional Connectivity and Its Relation to Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder
Resting-state functional MRI has been proposed as a new biomarker of prodromal neurodegenerative disorders, but it has been poorly investigated in the idiopathic form of rapid-eye-movement sleep behavior disorder (IRBD), a clinical harbinger of subsequent synucleinopathy. Particularly, a complex-network approach has not been tested to study brain functional connectivity in IRBD patients.
Comparative Cognitive Effects of Choreographed Exercise and Multimodal Physical Therapy in Older Adults With Amnestic Mild Cognitive Impairment: Randomized Clinical Trial
Recent research on mild cognitive impairment (MCI) has primarily focused on searching for measures to prevent or delay the progression of MCI to dementia. Physical exercise has shown to be effective in the prevention of age-related cognitive decline in elderly adults with MCI.